Group Publications
*indicates corresponding author; #equal contribution

Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity

Tilak Kumar Gupta#, Sven Klumpe#, Karin Gries#, Steffen Heinz#, Wojciech Wietrzynski#, Norikazu Ohnishi, Justus Niemeyer, Benjamin Spaniol, Miroslava Schaffer, Anna Rast, Matthias Ostermeier, Mike Strauss, Jürgen M. Plitzko, Wolfgang Baumeister, Till Rudack, Wataru Sakamoto, Jörg Nickelsen, Jan M. Schuller*, Michael Schroda*, Benjamin D. Engel*

BioArxiv 2021

The molecular machine that forms the membranes of life!​


In an amazing 6-lab cooperation we managed to determine the structure and mechanism of the major thylakoid membrane biogenesis factor VIPP1. Our work shows how this green ESCRT-III oligomer mediates membrane remodelling and repair


We could contribute the structure of the artifical enzyme glycolyl-CoA carboxylase (GCC), a new-to-nature enzyme to this exciting study by Tobi's lab.

A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation

Marieke Scheffen, Daniel G Marchal, Thomas Beneyton, Sandra K Schuller, Melanie Klose, Christoph Diehl, Jessica Lehmann, Pascal Pfister, Martina Carrillo, Hai He, Selçuk Aslan, Niña S Cortina, Peter Claus, Daniel Bollschweiler, Jean-Christophe Baret, Jan M Schuller, Jan Zarzycki, Arren Bar-Even, Tobias J Erb.

Nature Catalysis 2021

Structural insights into photosystem II assembly

Jure Zabret#, Stefan Bohn#, Sandra K Schuller, Oliver Arnolds, Madeline Möller, Jakob Meier-Credo, Pasqual Liauw, Aaron Chan, Emad Tajkhorshid, Julian D Langer, Raphael Stoll, Anja Krieger-Liszkay, Benjamin D Engel, Till Rudack*, Jan M Schuller*, Marc M Nowaczyk*

Nature Plants 2021

 How to build a molecular water splitting machine?


The first structural information on the biogenesis of PSII. We trapped the attachment of the CP43 light harvesting module and determined the high-resolution structure of it. Our work answers how a not yet fully assembled, but already partially active molecular machine is protected from photo damage. Great cooperation with our friends in the Nowaczyk lab. Our future work on this topic is supported by the Walter Benz foundation.

Redox-coupled proton pumping drives carbon concentration in the photosynthetic complex I

Jan M Schuller*#, Patricia Saura#, Jacqueline Thiemann#, Sandra K Schuller, Ana P Gamiz-Hernandez, Genji Kurisu, Marc M Nowaczyk*, Ville RI Kaila*

Nature Communications 2020


Direct visualization of degradation microcompartments at the ER membrane

Sahradha Albert, Wojciech Wietrzynski, Chia-Wei Lee, Miroslava Schaffer, Florian Beck, Jan M Schuller, Patrice A Salomé, Jürgen M Plitzko, Wolfgang Baumeister, Benjamin D Engel

PNAS 2020

Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer

Jan M Schuller*, James A Birrell, Hideaki Tanaka, Tsuyoshi Konuma, Hannes Wulfhorst, Nicholas Cox, Sandra K Schuller, Jacqueline Thiemann, Wolfgang Lubitz, Pierre Sétif, Takahisa Ikegami, Benjamin D Engel, Genji Kurisu*, Marc M Nowaczyk*

Science 2019

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